TradingView report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
Why TLPH Stock slipped -1.94% Today — RQD Quant Desk Flash
Talphera Inc. (TLPH) carries a Roarable Rating of D- (Sell) with 36/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief)
Is TLPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Talphera Inc. (NASDAQ: TLPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 36/100 at a spot price of $1.01 (-1.94% 1D, market cap $53.5M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, TLPH ranks #573 in composite RQD confidence.
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief)
How does TLPH compare to PLRX and HYFT in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), TLPH carries a Roarable D- (36/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, PLRX (Pliant Therapeutics Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $53.2M) and HYFT (MindWalk Holdings Corp.) posts a D grade (45/100 RQD, P/E N/A, ROIC —, cap $53.8M). Among the 5-stock peer group, TLPH leads on earnings multiple (N/A) while TLPH leads on capital efficiency (-35.0% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for TLPH?
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Per TLPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001427925), Talphera Inc. generated $37.8M in revenue (-11.6% YoY), -$14.3M in net income, and -$11.4M in free cash flow against $29.7M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 2/9
FRED Regime × Technicals: 36% of 52W Range • RSI-14 at 34.6 (NEUTRAL RANGE)
Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a TLPH Turnaround Squeeze
While TLPH currently carries a cautious 36/100 (D-) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($1.14) and Max Pain ($1.06) forces dealer call-delta covering toward $1.65.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why TLPH Stock slipped -1.94% Today — RQD Quant Desk Flash
Talphera Inc. (TLPH) slipped -1.94% to $1.01, trading at 36% of its 52-week range ($0.69 – $1.57). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 36% of its 52-week range ($0.69 – $1.57) with RSI-14 at 34.6 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±8.5% around $1.01 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable D- (Sell) backed by 52% gross margin and $0 annual free cash flow.
Yahoo! Finance Canada report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
https://www.siam.in/ report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
Traders Union report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
Talphera, Inc. (Nasdaq: TLPH), ("Talphera"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings, today announced that Comp
NEPHRO study hits 75% enrollment with data expected by year-end.
Yahoo Finance coverage on TLPH stock catalysts, institutional flow, and earnings outlook.
Talphera (NASDAQ:TLPH) said it had reached 75% enrollment in its NEPHRO-CRRT registrational study and remains on track to complete enrollment later in 2026, as the company prepares for a potential commercial launch of it
With this continued progress, we believe we are well positioned to complete enrollment in the nephro CRRT study this year. As mentioned, in early March, we announced the attainment of the 50% enrollment milestone in the
Talphera (NASDAQ:TLPH) reported first-quarter financial results on Wednesday. The transcript from the company's first-quarter earnings call has been provided below. This transcript is brought to you by Benzinga APIs. For
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring TLPH)
- ✓Walkthrough of TLPH's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
TLPH Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on TLPH today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for TLPH. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (TLPH)
1. Head-to-Head Health Care Peer Comparison (TLPH vs. PLRX, HYFT, XLO, HRTX)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1016 tracked Health Care securities in the Roarable RQD universe, Talphera Inc. (TLPH) ranks #573 by composite RQD confidence (36/100, grade D-) and #735 by equity capitalization ($53.5M). Within this direct 5-issuer industry benchmark cohort, TLPH leads on earnings valuation at N/A trailing P/E, while TLPH leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. HYFT currently holds the highest overall quantitative score in the immediate peer group at 45/100 (D) compared with TLPH at 36/100 (D-).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| TLPH
ACTIVE
Talphera Inc. | D- | 36/100 | — | — | -35.0% | -1.94% | $53.5M | Benchmark Subject |
| PLRX Pliant Therapeutics Inc. | E | 34/100 | — | — | -35.0% | -2.29% | $53.2M | /plrx-vs-tlph → |
| HYFT MindWalk Holdings Corp. | D | 45/100 | — | — | — | -2.65% | $53.8M | /hyft-vs-tlph → |
| XLO Xilio Therapeutics Inc. | E | 25/100 | — | — | -35.0% | -0.50% | $52.8M | /xlo-vs-tlph → |
| HRTX Heron Therapeutics Inc. | E | 34/100 | — | 73.3% | -35.0% | +6.27% | $52.7M | /hrtx-vs-tlph → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001427925In its most recent audited fiscal period (FY2025, filed 2025-12-31), Talphera Inc. (TLPH) reported GAAP revenue of $37.8M (-11.6% vs. FY2024 revenue of $42.7M , and -20.2% cumulative change since FY2023) , GAAP net income of -$14.3M, operating cash flow of -$11.4M, and free cash flow of -$11.4M (+10.4% YoY). On the balance sheet, TLPH closed FY2025 with $29.7M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 2/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $37.8M | -$14.3M | -$11.4M | -$11.4M | $29.7M | — |
| FY2024 (FY) | 2024-12-31 | $42.7M | -$13.0M | -$12.7M | -$12.7M | $18.2M | — |
| FY2023 (FY) | 2023-12-31 | $47.3M | -$18.4M | -$17.5M | -$17.5M | — | — |
3. TLPH Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs TLPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, Talphera Inc. (NASDAQ: TLPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 36/100 at a spot price of $1.01 (-1.94% 1D, market cap $53.5M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, TLPH ranks #573 in composite RQD confidence.
How does TLPH compare to PLRX and HYFT in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), TLPH carries a Roarable D- (36/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, PLRX (Pliant Therapeutics Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $53.2M) and HYFT (MindWalk Holdings Corp.) posts a D grade (45/100 RQD, P/E N/A, ROIC —, cap $53.8M). Among the 5-stock peer group, TLPH leads on earnings multiple (N/A) while TLPH leads on capital efficiency (-35.0% ROIC).
What are the biggest fundamental strengths and SEC risk factors for TLPH?
Per TLPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001427925), Talphera Inc. generated $37.8M in revenue (-11.6% YoY), -$14.3M in net income, and -$11.4M in free cash flow against $29.7M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.
Where is TLPH trading relative to its 50-day, 200-day, and 52-week technical levels?
TLPH last traded at $1.01 (-1.94% on volume of 55,868 shares), positioning the stock -11.40% below its 50-day simple moving average ($1.14) and 0.00% above its 200-day simple moving average ($1.01). Across its 52-week range of $0.69 to $1.57, TLPH sits at the 36.4% percentile with a 14-day RSI of 34.6 (NEUTRAL RANGE) and an implied next-earnings move of ±8.5% ($1.00 to $1.10).
TLPH — Talphera Inc.: What the Facts Mean to a Prospective Investor
1. Roarable Rating Brief: What This Means to a Prospective Investor
TLPH carries an RQD Score of 42 out of 100, a letter grade of D-, and the verdict label "Roarable Sell — Vulnerable Balance Sheet & Flow." Across the five pillars:
- Fundamental Cash Engine: 8 / 20. The rating cites ROIC of -35% and an FCF yield of -20.46%. For a prospective investor, this indicates the business is currently consuming cash relative to its capital base rather than generating returns, so valuation support must come from future operating change rather than present cash generation.
- Whale 13F Flow: 9 / 20. The rating references institutional accumulation and options positioning. The source does not itemize holders, so the strength of this signal cannot be independently verified from the provided data.
- Insider Conviction: 3 / 20. The rating references SEC Form 4 and Congressional PTR cluster flow. This is the weakest pillar and suggests limited insider-level conviction in the current setup.
- Macro Regime Fit: 12 / 20. The rating lists Beta of 1.0 and sector sensitivity. A beta of 1.0 means the stock is expected to move in line with the broad market; the rating treats this as a moderate fit.
- Forensic Balance Sheet: 10 / 20. The rating cites Altman Z of 2.5, Piotroski F of 2/9, and Debt/Equity of 0.5. The weak Piotroski reading is the key vulnerability flagged.
Investor implications (analytical, not personalized advice): the upside case depends on a reversal in cash burn and a stabilization of the balance sheet; the valuation tradeoff is that the price of $1.03 sits against a market capitalization of $55.5M and negative cash returns, leaving little current fundamental anchor. Second-order risk is concentrated in the weakest pillars (insider conviction and cash engine).
2. Business Model, Unit Margins & SEC Financial Trajectory
Talphera Inc. (TLPH) is a NASDAQ-listed issuer in the Health Care sector, operating in the Biotechnology: Pharmaceutical Preparations industry..1B. —: specific products, customers, or revenue model. The reported revenue of — across the SEC financial periods indicates no reported revenue in the source data.
Operating and net losses appear in each reported period, with gross, operating, and net margins all shown as 0% in the market data. ROIC is -35%, and the forensic pillar cites an Altman Z of 2.5 and a Piotroski F of 2/9, with Debt/Equity of 0.5. Cash declined from $8.9M to $5.9M between FY 2024 and FY 2025. —: EPS and debt values for the reported periods.
3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff
- 🐂 Primary Bull Case: The 0% dividend yield and beta of 1.0 mean the stock trades in line with the market, with a 52-week low of $0.69 leaving the current $1.03 price well above that floor. With Fundamental Cash Engine at 8/20 (ROIC -35.0%, FCF yield -20.46%) and Institutional Whale Flow at 5/20, sustained execution supports upside toward the top of the $0.69 – $1.57 52-week range.
- 🐻 Primary Bear Case: Negative ROIC of -35%, FCF yield of -20.46%, and an insider conviction pillar score of 3/20 point to ongoing cash burn without insider support. Investors must weigh current valuation against — operating margins and a 1.00 macro beta if sector demand softens.
4. 2nd-Order Butterfly Ripples & Key Questions to Watch
—: upstream suppliers, downstream customers, or sector correlations. A prospective investor should monitor the cash decline across FY 2024 to FY 2025 as the primary second-order pressure point.
- Key Question #1: What specific products or clinical programs generate the company's current spending, and what is their stage?
- Key Question #2: What is the company's runway given cash of $5.9M against FY 2025 free cash flow of -$11.4M?
- Key Question #3: Which institutions hold the stock, and what are the sizes and direction of their 13F positions?
TLPH Live News Feed, Press Releases & Catalyst Wire
Real-time company headlines, analyst actions, and sector developments for Talphera Inc. (TLPH) • Click "Debate This Headline" to argue it in the Roar Pit below
TradingView report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
Yahoo! Finance Canada report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
https://www.siam.in/ report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
Traders Union report covering Talphera Inc. (TLPH) market action, institutional positioning, and fundamental catalysts.
Talphera, Inc. (Nasdaq: TLPH), ("Talphera"), a specialty pharmaceutical company focused on the development and commercialization of innovative therapies for use in medically supervised settings, today announced that Comp
NEPHRO study hits 75% enrollment with data expected by year-end.
Yahoo Finance coverage on TLPH stock catalysts, institutional flow, and earnings outlook.
Talphera (NASDAQ:TLPH) said it had reached 75% enrollment in its NEPHRO-CRRT registrational study and remains on track to complete enrollment later in 2026, as the company prepares for a potential commercial launch of it
TLPH Bull vs. Bear Conversation Board — What's Your Call at $1.01?
The 0% dividend yield and beta of 1.0 mean the stock trades in line with the market, with a 52-week low of $0.69 leaving the current $1
Don't sleep on TLPH's setup in Health Care. The 0% dividend yield and beta of 1.0 mean the stock trades in line with the market, with a 52-week low of $0.69 leaving the current $1.03 price well above that floor.. Beta of 1.0 means it moves fast when momentum turns, and the 5-pillar RQD gauge (36/100) backs up the fundamental quality.
@MeanReversion_88 Shorting a 5/20 institutional whale-flow stock at $1.03 is dangerous when funds are rotating into Health Care.
Negative ROIC of -35%, FCF yield of -20.46%, and an insider conviction pillar score of 3/20 point to ongoing cash burn without insider
Fading this rally in TLPH at $1.03. Negative ROIC of -35%, FCF yield of -20.46%, and an insider conviction pillar score of 3/20 point to ongoing cash burn without insider support.. With a beta of 1.0 and the stock sitting at $1.03 (52-wk range $0.69–$1.57), the easy multiple expansion is already priced in.