Talphera Inc. (TLPH) 12-Month Stock Forecast & Price Target Cone

$1.03 -3.74% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $1.02

Talphera Inc. (TLPH) carries a Roarable Rating of D- (Sell) with 36/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE D- • RED ALERT Cap $53.5M
📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is TLPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Talphera Inc. (NASDAQ: TLPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 36/100 at a spot price of $1.03 (-3.74% 1D, market cap $53.5M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, TLPH ranks #573 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does TLPH compare to PLRX and HYFT in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), TLPH carries a Roarable D- (36/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, PLRX (Pliant Therapeutics Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $53.2M) and HYFT (MindWalk Holdings Corp.) posts a D grade (45/100 RQD, P/E N/A, ROIC —, cap $53.8M). Among the 5-stock peer group, TLPH leads on earnings multiple (N/A) while TLPH leads on capital efficiency (-35.0% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for TLPH?
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Per TLPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001427925), Talphera Inc. generated $0 in revenue, -$14.3M in net income, and -$11.4M in free cash flow against $29.7M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
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INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $1.02 (-0.86%)🧬 Dilution Drag (+2.48% YoY Shares)⚙️ Cash Engine: 8/20 (D-) • 0% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record Warning: Scores below 50 (36/100 · D-) historically underperformed SPY in 71% of rolling 90-day windows (-8.3% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →
RQD QUANT TACHOMETERRED ALERT • D-
025507510036
3-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw E · Rk D
Cash (8)Whales (5)SEC (10)Macro (10)CEO (3)
Each axis scored 0–20
12M PRICE TARGET CONE-9.7% Base Target
$2 Bull$1 Base$1 Bear
📬 FREE TLPH RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for TLPH)Realized 20D OHLCV Swing Band: ±8.5%
Deterministic 5-Pillar Attribution (36/100 Composite)
🔍 WHY TLPH SCORES 36/100 (D-) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (28% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 2/9

▲ #2 Bullish Driver: Macro Regime Fit+10/20 pts (28% of score)

FRED Regime × Technicals: 39% of 52W Range • RSI-14 at 34.6 (NEUTRAL RANGE)

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution4/20 pts (-16 pt drag)

Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
44
Grade D$1.08+0% Next Q
Q2 (-2Q)
41
Grade D$1.08-0.9% Next Q
Q3 (-1Q)
39
Grade E$1.07-3.7% Next Q
Current
36
Grade D-$1.03-8.3% Hist 90D α
Trajectory: D (44) → D- (36)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a TLPH Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While TLPH currently carries a cautious 36/100 (D-) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($1.14) and Max Pain ($1.08) forces dealer call-delta covering toward $1.65.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $TLPH• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “TLPH Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
INTERACTIVE 12-MONTH POSITION SIMULATOR

Drag to Test Your TLPH Position Size: $10,000

Shares at $1.03: 9708.7 sh
$1,000$10,000$25,000$50,000$100,000
12M Bear Case FloorTarget $0.73
$7,087
$-2,913 (-29.1%)
12M Consensus BaseTarget $0.93
$9,029
$-971 (-9.7%)
12M Bull Case BreakoutTarget $1.65
$16,019
+$6,019 (+60.2%)

Wall Street Analyst Breakdown & Historical Accuracy Audit (35 Desks)

Street Historical Accuracy: 64/100
● Strong Buy / Buy: 17● Hold: 9● Sell: 9
Wall Street FirmStance12M Target1Y AccuracyTrack Grade
Morgan StanleyInstitutional Equity DeskHOLD$174%A
Goldman SachsSector Coverage LeadUNDERPERFORM$269%B
JP MorganUS Large-Cap ResearchSELL$158%C
ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring TLPH)

  • ✓Walkthrough of TLPH's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
  • ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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TLPH // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: +15.73%🛡️ HOLDING TREND SUPPORT
2026-11-03O $1.07H $1.07L $1.03C $1.03VOL 83.5K
RES: $1.10SUP: $1.00SMA50: $1.14SMA200: $1.01
$1.55$1.34$1.12$0.91$0.69RES $1.10SUP $1.00$1.032026-05-042026-06-172026-08-042026-09-172026-11-03
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

TLPH Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
8.0%/yr Implied 5Y Growth

vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on TLPH today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for TLPH. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for TLPH today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (TLPH)

Health Care Rank #573 of 1016 ⚔️ PLRX vs TLPH Full Matrix →

1. Head-to-Head Health Care Peer Comparison (TLPH vs. PLRX, HYFT, XLO, HRTX)

Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, Talphera Inc. (TLPH) ranks #573 by composite RQD confidence (36/100, grade D-) and #735 by equity capitalization ($53.5M). Within this direct 5-issuer industry benchmark cohort, TLPH leads on earnings valuation at N/A trailing P/E, while TLPH leads on capital efficiency and profitability with -35.0% ROIC and — gross margin. HYFT currently holds the highest overall quantitative score in the immediate peer group at 45/100 (D) compared with TLPH at 36/100 (D-).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
TLPH ACTIVE
Talphera Inc.
D- 36/100 — — -35.0% -3.74% $53.5M Benchmark Subject
PLRX
Pliant Therapeutics Inc.
E 34/100 — — -35.0% -0.13% $53.2M /plrx-vs-tlph →
HYFT
MindWalk Holdings Corp.
D 45/100 — — — -5.83% $53.8M /hyft-vs-tlph →
XLO
Xilio Therapeutics Inc.
E 25/100 — — -35.0% +3.35% $52.8M /xlo-vs-tlph →
HRTX
Heron Therapeutics Inc.
E 34/100 — 73.3% -35.0% -5.67% $52.7M /hrtx-vs-tlph →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001427925

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Talphera Inc. (TLPH) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 ) , GAAP net income of -$14.3M, operating cash flow of -$11.4M, and free cash flow of -$11.4M (+10.4% YoY). On the balance sheet, TLPH closed FY2025 with $29.7M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 2/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $0 -$14.3M -$11.4M -$11.4M $29.7M —
FY2024 (FY) 2024-12-31 $0 -$13.0M -$12.7M -$12.7M $18.2M —
FY2023 (FY) 2023-12-31 $0 -$18.4M -$17.5M -$17.5M — —

3. TLPH Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is TLPH stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-03, Talphera Inc. (NASDAQ: TLPH) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 36/100 at a spot price of $1.03 (-3.74% 1D, market cap $53.5M). Pillar breakdown: Fundamental Cash Engine 8/20, Institutional 13F & Options Flow 5/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 10/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, TLPH ranks #573 in composite RQD confidence.

How does TLPH compare to PLRX and HYFT in the Health Care sector?

Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), TLPH carries a Roarable D- (36/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, PLRX (Pliant Therapeutics Inc.) holds a E grade (34/100 RQD, P/E N/A, ROIC -35.0%, cap $53.2M) and HYFT (MindWalk Holdings Corp.) posts a D grade (45/100 RQD, P/E N/A, ROIC —, cap $53.8M). Among the 5-stock peer group, TLPH leads on earnings multiple (N/A) while TLPH leads on capital efficiency (-35.0% ROIC).

What are the biggest fundamental strengths and SEC risk factors for TLPH?

Per TLPH's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001427925), Talphera Inc. generated $0 in revenue, -$14.3M in net income, and -$11.4M in free cash flow against $29.7M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is TLPH trading relative to its 50-day, 200-day, and 52-week technical levels?

TLPH last traded at $1.03 (-3.74% on volume of 83,509 shares), positioning the stock -9.65% below its 50-day simple moving average ($1.14) and +1.98% above its 200-day simple moving average ($1.01). Across its 52-week range of $0.69 to $1.57, TLPH sits at the 38.6% percentile with a 14-day RSI of 34.6 (NEUTRAL RANGE) and an implied next-earnings move of ±8.5% ($1.00 to $1.12).

TLPH Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

What is TLPH's 12-month stock price target?

Talphera Inc. (TLPH) carries a 12-month consensus base price target of $0.93 (-9.7% from $1.03), with a bull-case target of $1.65 and a bear-case floor of $0.73.

Is TLPH stock a Buy, Hold, or Sell right now?

Roarable's 5-Pillar RQD Quant Engine rates TLPH D- (Sell — SELL) with an RQD Confidence score of 36/100.

ROARABLE RATING BRIEF • RQD 36/100 (D-) ✓ STAGE-C NUMBER FIREWALL VERIFIED

TLPH — Talphera Inc.: What the Facts Mean to a Prospective Investor

Engine: anthropic/claude-haiku-5.5
As of: 2026-11-02T15:46:29Z

Roarable Rating Brief: What This Means to a Prospective Investor

Per the Roarable RQD rating, TLPH carries an RQD Score of 42 out of 100, a letter grade of D-, and the verdict label "Roarable Sell — Vulnerable Balance Sheet & Flow." Across the five pillars:

  • Fundamental Cash Engine: 8 / 20. The rating cites ROIC of -35% and an FCF yield of -20.46%. For a prospective investor, this indicates the business is currently consuming cash relative to its capital base rather than generating returns, so valuation support must come from future operating change rather than present cash generation.
  • Whale 13F Flow: 9 / 20. The rating references institutional accumulation and options positioning. The source does not itemize holders, so the strength of this signal cannot be independently verified from the provided data.
  • Insider Conviction: 3 / 20. The rating references SEC Form 4 and Congressional PTR cluster flow. This is the weakest pillar and suggests limited insider-level conviction in the current setup.
  • Macro Regime Fit: 12 / 20. The rating lists Beta of 1.0 and sector sensitivity. A beta of 1.0 means the stock is expected to move in line with the broad market; the rating treats this as a moderate fit.
  • Forensic Balance Sheet: 10 / 20. The rating cites Altman Z of 2.5, Piotroski F of 2/9, and Debt/Equity of 0.5. The weak Piotroski reading is the key vulnerability flagged.

Investor implications (analytical, not personalized advice): the upside case depends on a reversal in cash burn and a stabilization of the balance sheet; the valuation tradeoff is that the price of $1.03 sits against a market capitalization of $55.5M and negative cash returns, leaving little current fundamental anchor. Second-order risk is concentrated in the weakest pillars (insider conviction and cash engine).

Business

Talphera Inc. (TLPH) is a NASDAQ-listed issuer in the Health Care sector, operating in the Biotechnology: Pharmaceutical Preparations industry. Per the profile, the company has a market capitalization of $0.1B. Not available in source data: specific products, customers, or revenue model. The reported revenue of $0.0M across the SEC financial periods indicates no reported revenue in the source data.

Financial Trend

PeriodRevenueOperating IncomeNet IncomeEPSFCFCashDebt
FY 2025$0.0M$-13.5M$-14.3MN/A$-11.4M$5.9MN/A
FY 2024$0.0M$-15.3M$-13.0MN/A$-12.7M$8.9MN/A
FY 2023$0.0M$-16.9M$-18.4MN/A$-17.5MN/AN/A

Per the SEC financials, operating and net losses appear in each reported period, with gross, operating, and net margins all shown as 0% in the market data. Per the Roarable RQD rating, ROIC is -35%, and the forensic pillar cites an Altman Z of 2.5 and a Piotroski F of 2/9, with Debt/Equity of 0.5. Cash declined from $8.9M to $5.9M between FY 2024 and FY 2025. Not available in source data: EPS and debt values for the reported periods.

Recent Catalysts & News Wire Analysis

The four news items are all headlined as TradingView, Yahoo Finance, Index Put Call, and Traders Union coverage of TLPH, each flagged YELLOW with a MARKET WIRE impact label. Per those items, the content is generic market and positioning coverage. Not available in source data: any specific clinical, regulatory, financing, or partnership catalyst. Risk watch item: the sole price-level reference in the news (a $1.08 tick) sits above the current $1.03 price. The Butterfly Supply-Chain Graph lists no proprietary signals.

Butterfly Effect: 2nd-Order Supply-Chain & Sector Ripples

Per the Butterfly Supply-Chain Graph, the supply chain is "NONE," with no butterfly links. Not available in source data: upstream suppliers, downstream customers, or sector correlations. A prospective investor should monitor the cash decline across FY 2024 to FY 2025 as the primary second-order pressure point.

Open Questions

  • What specific products or clinical programs generate the company's current spending, and what is their stage?
  • What is the company's runway given cash of $5.9M against FY 2025 free cash flow of $-11.4M?
  • What is the debt position, since the source shows debt as N/A for all periods?
  • Which institutions hold the stock, and what are the sizes and direction of their 13F positions?
  • What financing, dilution, or partnership events are scheduled that could alter the share count or cash position?

TLPH Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for Talphera Inc. (TLPH) • Click "Debate This Headline" to argue it in the Roar Pit below

💬 Jump to TLPH Debate Forum (3) ↓
🟡 MARKET WIRE Yahoo Finance • 82d ago
Talphera Q2 Earnings Call Highlights

Talphera (NASDAQ:TLPH) said it had reached 75% enrollment in its NEPHRO-CRRT registrational study and remains on track to complete enrollment later in 2026, as the company prepares for a potential commercial launch of it

Read Full Source ↗
🔥 THE ROAR PIT • LIVE COMMUNITY DEBATE 3 Active Posts & Replies

TLPH Bull vs. Bear Conversation Board — What's Your Call at $1.03?

🐂 33% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON TLPH 🐻 67% BEARISH CONVICTION
1. Pick Your Side on TLPH:
💡 Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
RO RoarDesk_Moderator Roarable Research Desk 🐻 BEARISH 🎯 Target: $0.91 (-11.7%)
📌 Pinned Debate

🔥 Official Bull vs. Bear Debate: Is TLPH (D- • RQD 42/100) a Buy at $1.03?

Welcome to the TLPH (Talphera Inc.) Roar Pit. Current RQD Composite is 42/100 (Roarable Sell — Vulnerable Balance Sheet & Flow) in Biotechnology: Pharmaceutical Preparations. Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (🐂 Bull or 🐻 Bear) and drop your price target below.

MU MultipleCompression Forensic Accounting Watch 🐻 BEARISH 🎯 Target: $0.78 (-24.3%)
Spot @ $1.03

Pump the brakes on TLPH — check the valuation vs. margin headwinds

Everyone in here is repeating the bull case on TLPH, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless Talphera Inc. expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.

DE DeltaGamma_99 Verified K Arena Trader 🐂 BULLISH 🎯 Target: $1.31 (+27.2%)
Spot @ $1.03

TLPH cash flow & RQD setup is being underpriced by the Street here

Looking at the 5-pillar RQD breakdown on TLPH, the market is fixating on short-term headline noise in Biotechnology: Pharmaceutical Preparations and ignoring the balance sheet and cash flow trajectory. At $1.03 (52-wk range $0.69 - $1.57), any beat on forward guidance forces shorts and underweight funds to chase.

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