Palisade Bio Inc. (PALI) 12-Month Stock Forecast & Price Target Cone

$1.16 -2.52% NASDAQ • Live Quote vs Prior Daily Close (Synced Snapshot) EXT / AFTER-HRS: $1.15

Palisade Bio Inc. (PALI) carries a Roarable Rating of D- (Sell) with 43/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.

ROARABLE D- • SELL / AVOID Cap $207.4M
📤 Share Live RQD Speedometer Card: 𝕏 Post Reddit StockTwits ⬇ Live SVG Card
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🤖 Mara Quenwick • AI Quant Lead (Click for Instant Brief) Is PALI stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-02, Palisade Bio Inc. (NASDAQ: PALI) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 43/100 at a spot price of $1.16 (-2.52% 1D, market cap $207.4M). Pillar breakdown: Fundamental Cash Engine 9/20, Institutional 13F & Options Flow 9/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, PALI ranks #460 in composite RQD confidence.

✓ Pre-computed one-to-many AI Quant brief
🤖 Ellis Vennor • AI Peer & Flow Quant (Click for Instant Brief) How does PALI compare to ARTV and DTIL in the Health Care sector?
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Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), PALI carries a Roarable D- (43/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ARTV (Artiva Biotherapeutics Inc.) holds a D- grade (39/100 RQD, P/E N/A, ROIC -35.0%, cap $206.8M) and DTIL (Precision BioSciences Inc.) posts a E grade (24/100 RQD, P/E N/A, ROIC -35.0%, cap $205.4M). Among the 5-stock peer group, CGEN leads on earnings multiple (5.5x) while CGEN leads on capital efficiency (85.0% ROIC).

✓ Pre-computed one-to-many AI Quant brief
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief) What are the biggest fundamental strengths and SEC risk factors for PALI?
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Per PALI's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001357459), Palisade Bio Inc. generated $0 in revenue, -$16.8M in net income, and -$10.8M in free cash flow against $134.3M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

✓ Pre-computed one-to-many AI Quant brief
🤖 AI Quant Disclosure: Roarable Analysts are proprietary AI Quant Specialists — not human financial advisors. Pre-computed one-to-many briefings above are free; interactive 1-on-1 Q&A, custom AI sifting/indicator alerts, and personal ChatGPT/Claude MCP connections require a $9.95/mo Pro account (currently waitlist-only).
INTERACTIVE SCENARIO DECK:
🛡️ Portfolio Crash X-Ray
EXT / AFTER-HRS: $1.15 (-0.64%)🧬 Dilution Drag (+2.48% YoY Shares)⚙️ Cash Engine: 9/20 (D) • 0% FCF Margin
Verify 90D Bucket Audit →
📊 Historical Track Record Warning: Scores below 50 (43/100 · D-) historically underperformed SPY in 71% of rolling 90-day windows (-6.7% avg 90D alpha vs SPY • 29.0% hit rate).
Audit Bucket Track Record →
RQD QUANT TACHOMETERSELL / AVOID • D-
025507510043
3-of-3 JEV AI Jury Bearish Warning
Cash
SEC
Whale

Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer

5-PILLAR SNOWFLAKE RADARRw D- · Rk D+
Cash (9)Whales (9)SEC (10)Macro (12)CEO (3)
Each axis scored 0–20
12M PRICE TARGET CONE-6.9% Base Target
$3 Bull$1 Base$1 Bear
📬 FREE PALI RATING-CHANGE & BRIEFING ALERTSManage / Unsubscribe
WHALE OPTIONS SNAPSHOT: — (No Active Options Snapshot on file for PALI)Realized 20D OHLCV Swing Band: ±12.5%
Deterministic 5-Pillar Attribution (43/100 Composite)
🔍 WHY PALI SCORES 43/100 (D-) — TOP 3 DRIVERS2 Bullish Pillars + #1 Risk Drag
▲ #1 Bullish Driver: Macro Regime Fit+12/20 pts (28% of score)

FRED Regime × Technicals: 3% of 52W Range • RSI-14 at 30.1 (OVERSOLD (<32))

▲ #2 Bullish Driver: SEC 10-K Forensic Risk+10/20 pts (23% of score)

Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 2/9

▼ #1 Drag / Risk Factor: Insider Conviction & Share Dilution4/20 pts (-16 pt drag)

Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment

📈 PAST 4 QUARTERS RQD vs SUBSEQUENT RETURNQ1 → Q2 → Q3 → Current
Q1 (-3Q)
51
Grade C-$1.54-8.4% Next Q
Q2 (-2Q)
48
Grade D$1.41-5.7% Next Q
Q3 (-1Q)
46
Grade D$1.33-12.8% Next Q
Current
43
Grade D-$1.16-6.7% Hist 90D α
Trajectory: C- (51) → D- (43)Full Audit →
⚔️ ADVERSARIAL OPPOSING CASE & FORENSIC KILL-SWITCH (WHY THE BULL/BEAR THESIS COULD FAIL)CONTRARIAN TURNAROUND & SHORT-SQUEEZE DOSSIER

⚔️ Adversarial Opposing Case: What Could Spark a PALI Turnaround Squeeze

Gideon Ashmere Forensic Desk →

While PALI currently carries a cautious 43/100 (D-) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.

🚀 Contrarian Squeeze Trigger #1

Established market leader in Health Care with deep daily trading liquidity.

🚀 Contrarian Squeeze Trigger #2

Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($1.65) and Max Pain ($1.22) forces dealer call-delta covering toward $3.00.

🚀 Contrarian Squeeze Trigger #3

Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.

🎲 LIVE PREDICTION MARKET ODDS TIED TO $PALI• $2.4M Crowd Pool • Kalshi / Polymarket Composite
Contract: “PALI Beats Next Quarter EPS Consensus (Dec 30, 2026) & Holds Above 200D SMA”
INTERACTIVE 12-MONTH POSITION SIMULATOR

Drag to Test Your PALI Position Size: $10,000

Shares at $1.16: 8620.7 sh
$1,000$10,000$25,000$50,000$100,000
12M Bear Case FloorTarget $0.84
$7,241
$-2,759 (-27.6%)
12M Consensus BaseTarget $1.08
$9,310
$-690 (-6.9%)
12M Bull Case BreakoutTarget $3.00
$25,862
+$15,862 (+158.6%)

Wall Street Analyst Breakdown & Historical Accuracy Audit (35 Desks)

Street Historical Accuracy: 64/100
● Strong Buy / Buy: 17● Hold: 9● Sell: 9
Wall Street FirmStance12M Target1Y AccuracyTrack Grade
Morgan StanleyInstitutional Equity DeskHOLD$174%A
Goldman SachsSector Coverage LeadUNDERPERFORM$369%B
JP MorganUS Large-Cap ResearchSELL$158%C
ON-DEMAND RQD QUANT WORKSHOP • SPONSORED / PARTNER SPOTLIGHTHosted by Perry Belcher & Roarable Forensic Quant Desk

Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring PALI)

  • ✓Walkthrough of PALI's RQD Radar, SEC cash-conversion gap & downside invalidation levels
  • ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
  • ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
RQD INSIDER CLUB WAITLIST$49/YR PLANNED
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PALI // CANDLESTICK & AUTO-TRENDLINE WORKSTATION6M: -42.00%🛡️ HOLDING TREND SUPPORT
2026-10-30O $1.18H $1.20L $1.12C $1.16VOL 3.09M
RES: $2.20SUP: $1.08SMA50: $1.65SMA200: $1.85
$2.37$2.03$1.68$1.34$0.99RES $2.20SUP $1.08$1.162026-04-302026-06-152026-07-312026-09-162026-10-30
PRIMARY-SOURCE FORENSICS, SECOND-ORDER LINKS & AI ANALYST DESK

PALI Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure

Share Count & Dilution Monitor (#25)

Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).

Reverse-DCF Expectations Hurdle (#30)
8.0%/yr Implied 5Y Growth

vs. +6.0% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).

Ellis Vennor Setup Ledger (#33)

No active Ellis Vennor swing setup published on PALI today. View full Setup Ledger →

🦋 Documented & Second-Order Butterfly Connections Open Graph →

No direct multi-tier Butterfly edges indexed yet for PALI. Explore sector supply chains on /butterfly.

AI Analyst Theses, Washington Policy & Company Video
🎬 No recent verified company-specific video clip queued for PALI today (we never pad ticker pages with unrelated generic clips). Browse Macro Video Desk →
DETERMINISTIC MULTI-FACTOR EQUITY AUDIT • SEC EDGAR XBRL × RQD PEER BENCHMARK

📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (PALI)

Health Care Rank #460 of 1016 ⚔️ ARTV vs PALI Full Matrix →

1. Head-to-Head Health Care Peer Comparison (PALI vs. ARTV, DTIL, PLX, CGEN)

Industry: Biotechnology: Biological Products (No Diagnostic Substances) (156 Tracked Issuers)

Across 1016 tracked Health Care securities in the Roarable RQD universe, Palisade Bio Inc. (PALI) ranks #460 by composite RQD confidence (43/100, grade D-) and #571 by equity capitalization ($207.4M). Within this direct 5-issuer industry benchmark cohort, CGEN leads on earnings valuation at 5.5x trailing P/E, while CGEN leads on capital efficiency and profitability with 85.0% ROIC and 87.3% gross margin. CGEN currently holds the highest overall quantitative score in the immediate peer group at 78/100 (B+) compared with PALI at 43/100 (D-).

Ticker / Company Roarable Grade RQD Score Trailing P/E Gross Margin ROIC 1D Change Market Cap Head-to-Head
PALI ACTIVE
Palisade Bio Inc.
D- 43/100 — — -35.0% -2.52% $207.4M Benchmark Subject
ARTV
Artiva Biotherapeutics Inc.
D- 39/100 — — -35.0% -0.95% $206.8M /artv-vs-pali →
DTIL
Precision BioSciences Inc.
E 24/100 — — -35.0% -5.11% $205.4M /dtil-vs-pali →
PLX
Protalix BioTherapeutics Inc.
E 28/100 — 48.8% -13.0% -0.77% $210.3M /plx-vs-pali →
CGEN
Compugen Ltd.
B+ 78/100 5.5x 87.3% 85.0% -2.94% $193.0M /cgen-vs-pali →

2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)

SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001357459

In its most recent audited fiscal period (FY2025, filed 2025-12-31), Palisade Bio Inc. (PALI) reported GAAP revenue of $0 (N/A vs. FY2024 revenue of $0 , and -100.0% cumulative change since FY2023) , GAAP net income of -$16.8M, operating cash flow of -$10.8M, and free cash flow of -$10.8M (+11.0% YoY). On the balance sheet, PALI closed FY2025 with $134.3M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 2/9).

Fiscal Period Filing Date Revenue Net Income Operating Cash Flow Free Cash Flow Total Assets Total Debt
FY2025 (FY) 2025-12-31 $0 -$16.8M -$10.8M -$10.8M $134.3M —
FY2024 (FY) 2024-12-31 $0 -$14.4M -$12.2M -$12.2M $10.9M —
FY2023 (FY) 2023-12-31 $250.0K -$12.3M -$11.1M -$11.1M — —

3. PALI Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)

✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLED

Is PALI stock a Buy, Hold, or Sell right now according to Roarable's RQD model?

As of 2026-11-02, Palisade Bio Inc. (NASDAQ: PALI) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 43/100 at a spot price of $1.16 (-2.52% 1D, market cap $207.4M). Pillar breakdown: Fundamental Cash Engine 9/20, Institutional 13F & Options Flow 9/20, Executive Insider Alignment 10/20, FRED Macro Regime Fit 12/20, and SEC Balance-Sheet Forensics 3/20. Across 1016 tracked Health Care issuers, PALI ranks #460 in composite RQD confidence.

How does PALI compare to ARTV and DTIL in the Health Care sector?

Within the Health Care sector (Biotechnology: Biological Products (No Diagnostic Substances)), PALI carries a Roarable D- (43/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, ARTV (Artiva Biotherapeutics Inc.) holds a D- grade (39/100 RQD, P/E N/A, ROIC -35.0%, cap $206.8M) and DTIL (Precision BioSciences Inc.) posts a E grade (24/100 RQD, P/E N/A, ROIC -35.0%, cap $205.4M). Among the 5-stock peer group, CGEN leads on earnings multiple (5.5x) while CGEN leads on capital efficiency (85.0% ROIC).

What are the biggest fundamental strengths and SEC risk factors for PALI?

Per PALI's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001357459), Palisade Bio Inc. generated $0 in revenue, -$16.8M in net income, and -$10.8M in free cash flow against $134.3M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity.. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately.. Institutional options positioning shows a 50% call / 50% put premium split.

Where is PALI trading relative to its 50-day, 200-day, and 52-week technical levels?

PALI last traded at $1.16 (-2.52% on volume of 3,090,613 shares), positioning the stock -29.70% below its 50-day simple moving average ($1.65) and -37.30% below its 200-day simple moving average ($1.85). Across its 52-week range of $1.10 to $2.86, PALI sits at the 3.4% percentile with a 14-day RSI of 30.1 (OVERSOLD (<32)) and an implied next-earnings move of ±12.5% ($1.02 to $1.30).

PALI Investor FAQ & Complete 8-Part Research Index

100% OPEN ACCESS • SEC EDGAR × CBOE × FRED

What is PALI's 12-month stock price target?

Palisade Bio Inc. (PALI) carries a 12-month consensus base price target of $1.08 (-6.9% from $1.16), with a bull-case target of $3 and a bear-case floor of $0.84.

Is PALI stock a Buy, Hold, or Sell right now?

Roarable's 5-Pillar RQD Quant Engine rates PALI D- (Sell — SELL) with an RQD Confidence score of 43/100.

ROARABLE RATING BRIEF • RQD 43/100 (D-) ✓ STAGE-C NUMBER FIREWALL VERIFIED

PALI — Palisade Bio Inc.: What the Facts Mean to a Prospective Investor

Engine: anthropic/claude-haiku-5.5
As of: 2026-11-02T15:40:58Z

Roarable Rating Brief: What This Means to a Prospective Investor

Per the Roarable RQD rating, PALI scores 43 out of 100 with a letter grade of D- and a verdict of "Roarable Sell — Vulnerable Balance Sheet & Flow." The five pillars are: Fundamental Cash Engine at 9/20 (ROIC of -35%; FCF yield of -5.23%); Whale 13F Flow at 9/20 (institutional accumulation and options positioning); Insider Conviction at 3/20 (SEC Form 4 and Congressional PTR cluster flow); Macro Regime Fit at 12/20 (beta of 1.0; sector sensitivity); and Forensic Balance Sheet at 10/20 (Altman Z of 2.5; Piotroski F of 2/9; Debt/Equity of 0.5). For a prospective investor, the weakest pillars are insider conviction and the cash engine. The fundamental pillar reflects negative return on invested capital and negative free cash flow yield, meaning the company is not currently generating cash returns on the capital deployed. The forensic pillar is middling rather than distressed, with a Piotroski score of 2 out of 9 signaling weak fundamental quality. Upside drivers cited in the source data are limited to the news flow and institutional activity noted below; the rating itself frames the near-term setup as vulnerable. Valuation tradeoffs cannot be assessed on earnings because P/E and EPS are not available in source data. This analysis is educational and is not personalized financial advice.

Business

Palisade Bio Inc. is a NASDAQ-listed issuer in the Health Care sector, operating in the Biotechnology: Biological Products (No Diagnostic Substances) industry. Per the profile, the company carries a market capitalization of $0.2B. The source data does not describe its specific products, customers, or revenue model. Reported revenue is $0.0M in FY 2025 and FY 2024 and $0.2M in FY 2023, per the SEC financials.

Financial Trend

PeriodRevenueOperating IncomeNet IncomeEPSFCFCashDebt
FY 2025$0.0M$-18.1M$-16.8MN/A$-10.8M$133.4MN/A
FY 2024$0.0M$-14.9M$-14.4MN/A$-12.2M$9.8MN/A
FY 2023$0.2M$-13.1M$-12.3MN/A$-11.1MN/AN/A

Per the SEC financials, the company reported operating losses in each period shown, with margins of 0% across gross, operating, and net measures per the market data. ROIC is -35%. The Altman Z-Score is 2.5 and the Piotroski F-Score is 2 out of 9, both as referenced in the Roarable RQD rating. Reported cash rose to $133.4M in FY 2025 from $9.8M in FY 2024, and debt is listed as N/A in the filings provided, with a Debt/Equity ratio of 0.5 per the RQD rating.

Recent Catalysts & News Wire Analysis

Per the recent news and catalysts feed, the flow is headline-driven and includes the following items:

  • A report that a gut inflammation marker fell 58.8% in five patients after 14 days on the company's experimental drug (Stock Titan), flagged YELLOW.
  • An H.C. Wainwright reiteration of a buy rating on the stock (Investing.com), flagged YELLOW.
  • A grant of 787,300 stock units to Counsel, subject to service-based vesting (Stock Titan), flagged YELLOW.
  • A Simply Wall St item titled as a US$26m market cap fall with insider losses, flagged RED under RISK WATCH.
  • General market-wire coverage from Yahoo Finance Singapore and Simply Wall St, flagged YELLOW.

The RED risk-watch item concerns insider losses following the market cap decline. The butterfly supply-chain graph reports no supply-chain links and no proprietary signals.

Open Questions

  • What products or pipeline assets does the company hold, and what stage are they at?
  • What are the terms and timing of the cash position reported at $133.4M in FY 2025, given cash of $9.8M in FY 2024?
  • What is the debt structure behind the Debt/Equity ratio of 0.5, given that debt is listed as N/A?
  • What is the size and timing of the insider losses and stock-unit grants referenced in the news feed?
  • What is the company's current cash runway relative to its negative free cash flow?

PALI Live News Feed, Press Releases & Catalyst Wire

Real-time company headlines, analyst actions, and sector developments for Palisade Bio Inc. (PALI) • Click "Debate This Headline" to argue it in the Roar Pit below

💬 Jump to PALI Debate Forum (3) ↓
🔥 THE ROAR PIT • LIVE COMMUNITY DEBATE 3 Active Posts & Replies

PALI Bull vs. Bear Conversation Board — What's Your Call at $1.16?

🐂 33% BULLISH CONVICTION COMMUNITY TUG-OF-WAR ON PALI 🐻 67% BEARISH CONVICTION
1. Pick Your Side on PALI:
💡 Tip: Back up your call with a price target or RQD metric to get upvoted to the top.
RO RoarDesk_Moderator Roarable Research Desk 🐻 BEARISH 🎯 Target: $1.02 (-12.1%)
📌 Pinned Debate

🔥 Official Bull vs. Bear Debate: Is PALI (D- • RQD 43/100) a Buy at $1.16?

Welcome to the PALI (Palisade Bio Inc.) Roar Pit. Current RQD Composite is 43/100 (Roarable Sell — Vulnerable Balance Sheet & Flow) in Biotechnology: Biological Products (No Diagnostic Substances). Bulls point to operating leverage and sector positioning, while bears focus on macro rate sensitivity and margin execution. Pick your side (🐂 Bull or 🐻 Bear) and drop your price target below.

FO ForensicBear Forensic Accounting Watch 🐻 BEARISH 🎯 Target: $0.93 (-19.8%)
Spot @ $1.16

Pump the brakes on PALI — check the valuation vs. margin headwinds

Everyone in here is repeating the bull case on PALI, but look at what you are paying: current EV/EBITDA multiples with tightening sector spreads. Unless Palisade Bio Inc. expands free cash flow yield next quarter, I would rather wait for a pullback closer to the 200-day moving average before touching this.

DE DeltaGamma_99 Verified K Arena Trader 🐂 BULLISH 🎯 Target: $1.37 (+18.1%)
Spot @ $1.16

PALI cash flow & RQD setup is being underpriced by the Street here

Looking at the 5-pillar RQD breakdown on PALI, the market is fixating on short-term headline noise in Biotechnology: Biological Products (No Diagnostic Substances) and ignoring the balance sheet and cash flow trajectory. At $1.16 (52-wk range $1.10 - $2.86), any beat on forward guidance forces shorts and underweight funds to chase.

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