Yahoo Finance report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Why AMLX Stock dropped -2.84% Today — RQD Quant Desk Flash
Amylyx Pharmaceuticals Inc. (AMLX) carries a Roarable Rating of D- (Sell) with 39/100 RQD Confidence due to weak cash-flow efficiency and sensitivity to current interest rates. Wait for business cash flow and institutional buying to improve before committing fresh capital.
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Is AMLX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
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As of 2026-11-03, Amylyx Pharmaceuticals Inc. (NASDAQ: AMLX) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 39/100 at a spot price of $28.04 (-2.84% 1D, market cap $3.62B). Pillar breakdown: Fundamental Cash Engine 6/20, Institutional 13F & Options Flow 10/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 10/20, and Executive Insider Alignment 3/20. Across 1015 tracked Health Care issuers, AMLX ranks #480 in composite RQD confidence.
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How does AMLX compare to XENE and OGN in the Health Care sector?
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Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), AMLX carries a Roarable D- (39/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XENE (Xenon Pharmaceuticals Inc.) holds a D- grade (37/100 RQD, P/E N/A, ROIC -35.0%, cap $3.62B) and OGN (Organon & Co.) posts a B- grade (70/100 RQD, P/E 19.4x, ROIC 24.9%, cap $3.63B). Among the 5-stock peer group, ACAD leads on earnings multiple (9.1x) while OGN leads on capital efficiency (24.9% ROIC).
🤖 Gideon Ashmere • AI SEC 10-K Forensics (Click for Instant Brief)
What are the biggest fundamental strengths and SEC risk factors for AMLX?
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Per AMLX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001658551), Amylyx Pharmaceuticals Inc. generated $429.2M in revenue (+391.3% YoY), -$144.7M in net income, and -$123.5M in free cash flow against $332.6M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Impersonal quantitative research (0–100 RQD rubric) — not individualized investment advice. Past performance does not guarantee future results. Full Disclaimer
20D Institutional Volume Accumulation (±9.6% realized swing band)
Altman Z-Score 3.80 (FORTRESS SAFE (>3.0)) • Piotroski F-Score 3/9
Dilution Drag (+2.48% YoY Shares) & executive Form 4 sales trim 16 pts from alignment
⚔️ Adversarial Opposing Case: What Could Spark a AMLX Turnaround Squeeze
While AMLX currently carries a cautious 39/100 (D-) rating due to Insider Conviction & Share Dilution (4/20), shorts face asymmetric squeeze risk if free cash flow inflects or management executes accretive buybacks.
Established market leader in Health Care with deep daily trading liquidity.
Options & Short-Covering Gamma: Reclaiming the 50-day SMA ($30.51) and Max Pain ($29.44) forces dealer call-delta covering toward $43.20.
Forensic Repair Trigger: Halting share dilution (Dilution Drag (+2.48% YoY Shares)) or retiring high-cost debt immediately upgrades the SEC 10-K Forensic pillar.
Why AMLX Stock dropped -2.84% Today — RQD Quant Desk Flash
Amylyx Pharmaceuticals Inc. (AMLX) dropped -2.84% to $28.04, trading at 57% of its 52-week range ($10.83 – $41.14). Stretched risk/reward at current multiples (-35% return on capital) under elevated 10-year interest-rate pressure.
- ▸Technical Tape: Trading at 57% of its 52-week range ($10.83 – $41.14) with RSI-14 at 51.9 (NEUTRAL RANGE).
- ▸Volatility Profile: Historical 20-day realized swing band of ±9.6% around $28.04 (no active unusual options sweep snapshot on file).
- ▸Fundamental Anchor: Roarable D- (Sell) backed by 52% gross margin and $0 annual free cash flow.
TradingView report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Simply Wall St report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Benzinga report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
MarketBeat report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Simply Wall St report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
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Citigroup analyst Geoff Meacham maintains Amylyx Pharmaceuticals (NASDAQ:AMLX) with a Buy and raises the price target from $32 to $39.
Red-Light Warning Desk: Spotting SEC Cash-Flow & Dilution Risks Before Downgrades (Featuring AMLX)
- ✓Walkthrough of AMLX's RQD Radar, SEC cash-conversion gap & downside invalidation levels
- ✓3 asymmetric Bear/Hedge frameworks when 10-year Treasury yields stay elevated
- ✓Includes nightly RQD rating-change & forensic signal email alerts on your tracked stocks
AMLX Dilution Monitor, Expectations Hurdle, Butterfly Connections & Policy Exposure
Multi-year comparable XBRL diluted share count not disclosed (ETF or recent listing).
vs. +391.3% actual YoY revenue growth (assuming 9.25% cost of equity & 16.5x terminal multiple).
No active Ellis Vennor swing setup published on AMLX today. View full Setup Ledger →
No direct multi-tier Butterfly edges indexed yet for AMLX. Explore sector supply chains on /butterfly.
📊 Quantitative Sector Peer Comparison, SEC Filing Delta & Investment FAQ (AMLX)
1. Head-to-Head Health Care Peer Comparison (AMLX vs. XENE, OGN, IRON, ACAD)
Industry: Biotechnology: Pharmaceutical Preparations (489 Tracked Issuers)Across 1015 tracked Health Care securities in the Roarable RQD universe, Amylyx Pharmaceuticals Inc. (AMLX) ranks #480 by composite RQD confidence (39/100, grade D-) and #190 by equity capitalization ($3.62B). Within this direct 5-issuer industry benchmark cohort, ACAD leads on earnings valuation at 9.1x trailing P/E, while OGN leads on capital efficiency and profitability with 24.9% ROIC and 53.3% gross margin. OGN currently holds the highest overall quantitative score in the immediate peer group at 70/100 (B-) compared with AMLX at 39/100 (D-).
| Ticker / Company | Roarable Grade | RQD Score | Trailing P/E | Gross Margin | ROIC | 1D Change | Market Cap | Head-to-Head |
|---|---|---|---|---|---|---|---|---|
| AMLX
ACTIVE
Amylyx Pharmaceuticals Inc. | D- | 39/100 | — | — | -35.0% | -2.84% | $3.62B | Benchmark Subject |
| XENE Xenon Pharmaceuticals Inc. | D- | 37/100 | — | — | -35.0% | +0.56% | $3.62B | /xene-vs-amlx → |
| OGN Organon & Co. | B- | 70/100 | 19.4x | 53.3% | 24.9% | -0.14% | $3.63B | /ogn-vs-amlx → |
| IRON Disc Medicine Inc. | D+ | 54/100 | — | — | -27.5% | -2.75% | $3.59B | /iron-vs-amlx → |
| ACAD ACADIA Pharmaceuticals Inc. | D | 49/100 | 9.1x | 91.7% | 7.9% | -0.58% | $3.55B | /acad-vs-amlx → |
2. Multi-Year SEC XBRL Revenue, Cash Flow & Balance-Sheet Trajectory (FY2023–FY2025)
SEC EDGAR 10-K • FILED 2025-12-31 • CIK 0001658551 ↗In its most recent audited fiscal period (FY2025, filed 2025-12-31), Amylyx Pharmaceuticals Inc. (AMLX) reported GAAP revenue of $429.2M (+391.3% vs. FY2024 revenue of $87.4M , and +12.7% cumulative change since FY2023) , GAAP net income of -$144.7M, operating cash flow of -$123.3M, and free cash flow of -$123.5M (+26.4% YoY). On the balance sheet, AMLX closed FY2025 with $332.6M in total assets against $0 in total debt (Altman Z-Score: N/A, Piotroski F-Score: 3/9).
| Fiscal Period | Filing Date | Revenue | Net Income | Operating Cash Flow | Free Cash Flow | Total Assets | Total Debt |
|---|---|---|---|---|---|---|---|
| FY2025 (FY) | 2025-12-31 | $429.2M | -$144.7M | -$123.3M | -$123.5M | $332.6M | — |
| FY2024 (FY) | 2024-12-31 | $87.4M | -$301.7M | -$167.6M | -$167.8M | $193.6M | — |
| FY2023 (FY) | 2023-12-31 | $380.8M | $49.3M | $11.9M | $11.9M | — | — |
3. AMLX Data-Verified Investor FAQ (RQD Rating, Sector Peers, SEC Forensics & Technicals)
✓ SCHEMA.ORG FAQPAGE JSON-LD ENABLEDIs AMLX stock a Buy, Hold, or Sell right now according to Roarable's RQD model?
As of 2026-11-03, Amylyx Pharmaceuticals Inc. (NASDAQ: AMLX) is rated D- (Sell / SELL) by Roarable's 5-pillar RQD engine with a composite confidence score of 39/100 at a spot price of $28.04 (-2.84% 1D, market cap $3.62B). Pillar breakdown: Fundamental Cash Engine 6/20, Institutional 13F & Options Flow 10/20, SEC Balance-Sheet Forensics 10/20, FRED Macro Regime Fit 10/20, and Executive Insider Alignment 3/20. Across 1015 tracked Health Care issuers, AMLX ranks #480 in composite RQD confidence.
How does AMLX compare to XENE and OGN in the Health Care sector?
Within the Health Care sector (Biotechnology: Pharmaceutical Preparations), AMLX carries a Roarable D- (39/100 RQD), trailing P/E of N/A, gross margin of —, and ROIC of -35.0%. By comparison, XENE (Xenon Pharmaceuticals Inc.) holds a D- grade (37/100 RQD, P/E N/A, ROIC -35.0%, cap $3.62B) and OGN (Organon & Co.) posts a B- grade (70/100 RQD, P/E 19.4x, ROIC 24.9%, cap $3.63B). Among the 5-stock peer group, ACAD leads on earnings multiple (9.1x) while OGN leads on capital efficiency (24.9% ROIC).
What are the biggest fundamental strengths and SEC risk factors for AMLX?
Per AMLX's SEC EDGAR XBRL 10-K filing (FY2025, filed 2025-12-31, CIK 0001658551), Amylyx Pharmaceuticals Inc. generated $429.2M in revenue (+391.3% YoY), -$144.7M in net income, and -$123.5M in free cash flow against $332.6M in total assets and $0 in total debt. Key quantitative strengths: Established market leader in Health Care with deep daily trading liquidity. Primary risk factors monitored: Company executives have done more routine share selling than personal cash buying lately. Institutional options positioning shows a 50% call / 50% put premium split.
Where is AMLX trading relative to its 50-day, 200-day, and 52-week technical levels?
AMLX last traded at $28.04 (-2.84% on volume of 1,161,875 shares), positioning the stock -8.10% below its 50-day simple moving average ($30.51) and +38.61% above its 200-day simple moving average ($20.23). Across its 52-week range of $10.83 to $41.14, AMLX sits at the 56.8% percentile with a 14-day RSI of 51.9 (NEUTRAL RANGE) and an implied next-earnings move of ±9.6% ($25.35 to $30.73).
AMLX — Amylyx Pharmaceuticals Inc.: What the Facts Mean to a Prospective Investor
1. Roarable Rating Brief: What This Means to a Prospective Investor
Amylyx Pharmaceuticals Inc. (AMLX) earns a live Roarable RQD composite score of 39/100, corresponding to a D- letter grade (Roarable Sell) at a spot price of $28.04 (-2.84% 1D, market capitalization $3.62B).
- Fundamental Cash Engine (6/20): Anchored by return on invested capital (ROIC) of -35.0%, gross margin of —, operating margin of —, and free cash flow yield of -3.43%.
- Whale 13F & Options Flow (10/20) + Insider Conviction (3/20): Tracks institutional 13F accumulation, CBOE options call/put positioning, and SEC Form 4 / Congressional PTR filings.
- Macro Regime Fit (10/20) + Forensic Balance Sheet (10/20): Incorporates a 1.00x equity beta, Altman Z-Score of N/A, Piotroski F-Score of 3/9, and Debt/Equity of N/A.
2. Business Model, Unit Margins & SEC Financial Trajectory
Amylyx Pharmaceuticals Inc. (AMLX) is a NASDAQ-listed issuer in the Health Care sector, operating in the Biotechnology: Pharmaceutical Preparations industry. The company carries a market capitalization of $3.6B per the market data. Reported revenue was $380.8M for FY 2023, $87.4M for FY 2024, and — for FY 2025. — describes the company's specific products, customers, or revenue model.
In its latest audited SEC EDGAR 10-K filing for FY2025 (filed 2025-12-31), Amylyx Pharmaceuticals Inc. (AMLX) reported $429.2M in annual revenue (up from $87.4M in FY2024, +391.3% YoY) and -$144.7M in GAAP net income. Over the multi-year SEC filing window from FY2023 ($380.8M revenue, $49.3M net income) through FY2025, AMLX scaled operating cash flow to -$123.3M and free cash flow to -$123.5M, backed by $332.6M in total assets against $0 in total debt.
3. Institutional Bull vs. Bear Thesis & Valuation Tradeoff
- 🐂 Primary Bull Case (D- • RQD 39/100): Established market leader in Health Care with deep daily trading liquidity. Free cash flow yield of -3.43% and institutional whale pillar of 10/20. With Fundamental Cash Engine at 6/20 and Institutional Whale Flow at 10/20, sustained execution supports upside toward the upper end of the $10.83 – $41.14 52-week range.
- 🐻 Primary Bear Case & Valuation Risk: Company executives have done more routine share selling than personal cash buying lately. Investors must weigh current valuation against — operating margins and a 1.00x macro beta.
4. 2nd-Order Butterfly Ripples & Key Questions to Watch
Sector and industry classifications are Health Care and Biotechnology: Pharmaceutical Preparations, but no sector correlation data is provided. No 2nd-order bottlenecks are identified in the source data.
- Key Question #1: Can AMLX sustain or expand its — operating margin and -35.0% ROIC against Biotechnology: Pharmaceutical Preparations peers over the next 4 quarters?
- Key Question #2: Following FY2025 revenue of $429.2M and free cash flow of -$123.5M, how will capital allocation balance growth reinvestment against $0 in total debt?
- Key Question #3: How sensitive is AMLX's equity valuation to Health Care capital spending cycles and macro interest-rate shifts (Beta 1.00x)?
AMLX Live News Feed, Press Releases & Catalyst Wire
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Yahoo Finance report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
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Simply Wall St report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Stock Titan report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Benzinga report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
TradingView report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
MarketBeat report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
Simply Wall St report covering Amylyx Pharmaceuticals Inc. (AMLX) market action, institutional positioning, and fundamental catalysts.
AMLX Bull vs. Bear Conversation Board — What's Your Call at $28.04?
A reported 12-month price target raised to $43 implies 59% upside from the current price, and reported cash increased to $226.7M in FY
The street is overcomplicating Amylyx Pharmaceuticals Inc. (AMLX). A reported 12-month price target raised to $43 implies 59% upside from the current price, and reported cash increased to $226.7M in FY 2025.. With an RQD score of 39/100 (D-) and Forensic Balance Sheet at 10/20, any positive earnings surprise or guidance raise forces underweight funds to chase above $31.17.
@MultipleCompression Fair point on current EV/EBITDA multiples, but you're ignoring the forward operating leverage in Biotechnology: Pharmaceutical Preparations. If gross margin (0.0%) holds, EPS grows into the multiple faster than bears think.
Reported net income fell to -$144.7M in FY 2025 with ROIC at -35% and FCF yield at -3.43%, while revenue dropped to $0.0M.
I respect the product at Amylyx Pharmaceuticals Inc., but the stock at $28.86 is a different story. Reported net income fell to -$144.7M in FY 2025 with ROIC at -35% and FCF yield at -3.43%, while revenue dropped to $0.0M.. FCF yield is -3.43% and RQD sits at 39/100 (D-) — why pay up here when you can wait for next quarter's numbers?