COMP <GO>
KRYS vs TWST // EV/EBITDA & P/E VALUATION
Krystal Biotech Inc. (NASDAQ) VS. Twist Bioscience Corporation (NASDAQ) • 15-METRIC TALLY: KRYS 7
— TWST 3
■ METRIC PARITY
LAST: $295.90 (-10.95%) • MKT CAP: $9.84B
valuation
53.4x
LAST: $129.04 (-15.54%) • MKT CAP: $10.13B
valuation
—
15-METRIC INSTITUTIONAL SIDE-BY-SIDE SCORECARD (KRYS VS. TWST)
EMERALD CELL = QUANTITATIVE EDGE
| INSTITUTIONAL METRIC | KRYS | TWST | SPREAD (A - B) | ADVANTAGE | DEDICATED URL |
|---|---|---|---|---|---|
| Gross Profit Margin | — | 94.20% | — | TIE | /gross-margins <GO> |
| Return on Invested Capital (ROIC) | 16.50% | -11.70% | +28.20 | KRYS | /roic <GO> |
| EV/EBITDA & P/E Valuation ACTIVE | 53.4x | — | — | TIE | /valuation <GO> |
| Free Cash Flow Yield | 1.97% | -0.66% | +2.63 | KRYS | /fcf-yield <GO> |
| Operating Margin | 41.50% | -4.20% | +45.70 | KRYS | /operating-margins <GO> |
| Net Profit Margin | 52.60% | -2.40% | +55.00 | KRYS | /net-margins <GO> |
| Revenue Growth (YoY) | 33.90% | 16.50% | +17.40 | KRYS | /revenue-growth <GO> |
| Dividend Yield & FCF Payout Safety | 0.00% | 0.00% | 0.00 | TIE | /dividend-safety <GO> |
| Altman Z-Score & Debt/Equity | 26.00 | 26.00 | 0.00 | TIE | /balance-sheet <GO> |
| Piotroski F-Score Quality | 8/9 | 6/9 | +2.00 | KRYS | /piotroski-score <GO> |
| Options Implied Move & Put/Call Skew | — | — | — | TIE | /options-implied-move <GO> |
| RSI-14 & 200D SMA Momentum | 53.8 | 48.4 | +5.40 | KRYS | /rsi-technicals <GO> |
| 10Y Yield & FRED Macro Beta | 0.91 | 0.98 | -0.07 | TWST | /macro-sensitivity <GO> |
| Forward P/E Multiple | 39.4x | 21.0x | +18.40 | TWST | /forward-pe <GO> |
| Enterprise Scale & Market Cap | $9.84B | $10.13B | -$294.1M | TWST | /market-cap <GO> |
5-YEAR HISTORICAL XBRL REVENUE & MARGIN TRAJECTORY SEC FORM 10-K FY
| FISCAL YEAR | KRYS REV | TWST REV | KRYS GROSS % | TWST GROSS % | KRYS FCF | TWST FCF |
|---|---|---|---|---|---|---|
| FY 2025 | $389.1M | $381.5M | — | — | $188.9M | -$75.6M |
| FY 2024 | $290.5M | $618.3M | — | — | $119.2M | -$69.2M |
| FY 2023 | $50.7M | $608.0M | — | — | -$91.1M | -$142.5M |
FRED MACRO REGIME CORRELATION COMPARISON PEARSON r
KRYS // BETA 0.91
TWST // BETA 0.98